losing a lot of weight will make your brain younger

(Image: Pixabay CC0)

Significant weight loss following bariatric surgery would make the brain about 5 years younger

It was known that bariatric surgery led to a spectacular improvement in cardiometabolic health indicators. Now, a study just published in the journal NeuroImage shows that it also brings substantial benefits to the brain. Indeed, 2 years after bariatric surgery, the brains of patients who benefited from this procedure “rejuvenated” by more than 5 years.
This is the finding of a Quebec research team led by Andréanne Michaud of the School of Nutrition and the Institute of Nutrition and Functional Foods at Laval University and the Research Centre of the Institut universitaire de cardiologie et de pneumologie de Québec. This team used three databases containing brain images to determine how well weight loss following bariatric surgery compensated for the premature aging of the brain associated with severe obesity.
Using the first database containing information on 640 normal-weight people, the researchers built a model to determine what constitutes a normal change in gray matter density with age. The second database, from the Human Connectome Project, compared the brains of 46 people with severe obesity to 46 people of the same gender, age, and ethnicity, but with normal weight.
“This allowed us to validate our model and confirm the findings of previous studies that reported that severe obesity was associated with changes in the brain,” notes Professor Michaud. Our analyses show that the observed brain age is about 7 years higher than the chronological age in people with severe obesity.”
The researchers then used their model to document the evolution of the brain in 32 patients who had undergone bariatric surgery at the Quebec Heart and Lung Institute – Laval University. The images were taken two months before surgery and 4, 12 and 24 months after surgery.

“The abnormalities observed in the brains of severely obese individuals may be corrected by significant weight loss and the subsequent improvement in cardiometabolic health.”

The analyses show that one year after surgery, the brains of these patients were 3 years younger. Two years after surgery, they were 5.6 years younger. “The brain age of these patients corresponded to what is observed in people of the same age with a normal weight,” notes Andréanne Michaud.
The greater the reduction in body mass index, blood pressure, and insulin resistance, the more pronounced the rejuvenation, the researchers found. “Our study suggests that the abnormalities observed in the brains of severely obese individuals may be corrected by significant weight loss and the subsequent improvement in cardiometabolic health,” summarized Professor Michaud.

The researcher and her team continue to follow these patients to determine whether the observed gains are sustained and whether they translate into improvement on tests measuring cognitive abilities.
The study published in NeuroImage is signed by Yashar Zeighami, Mahsa Dadar, Alain Dagher and Alan Evans, from McGill University, Stephanie Fulton, from the Université de Montréal, and by Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, André Tchernof, Denis Richard and Andréanne Michaud, from the Université de Montréal.Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, André Tchernof, Denis Richard and Andréanne Michaud, from the Institut universitaire en cardiologie et en pneumologie de Québec and Université Laval.

TECH NEWS RELATED

Could letting social media users rank accuracy help stop misinformation?

When fighting the spread of misinformation, social media platforms typically place most users in the passenger seat. Platforms often use machine-learning algorithms or human fact-checkers to flag false or misinforming content for users. “Just because this is the status quo doesn’t mean it is the correct way or the ...

View more: Could letting social media users rank accuracy help stop misinformation?

Defying Extinction – Asian Animals Found Thriving Near Humans

Sumatra tiger on the forest’s edge. Credit: UQ/Matthew Luskin Some of Asia’s largest animals, including tigers and elephants, are defying 12,000 years of extinction trends by coexisting with people, according to research led by the University of Queensland. Researchers combed through paleontological records to compare the past distribution of ...

View more: Defying Extinction – Asian Animals Found Thriving Near Humans

Stanford Researchers Find COVID-19 Pandemic Stress Physically Aged Teens’ Brains

The brains of adolescents who were assessed after the pandemic shutdowns ended appeared several years older than those of teens who were assessed before the pandemic. The brains of adolescents who were assessed after the COVID pandemic shutdowns ended appeared several years older than those of teens who were ...

View more: Stanford Researchers Find COVID-19 Pandemic Stress Physically Aged Teens’ Brains

“Time inequality” is the world’s real problem, not income inequality

According to the United Nations, the birth of the eight billionth person happened on November 15, 2022. Should we celebrate or mourn that milestone? Many see the expansion of the human enterprise as a calamity. Thinkers from Thomas Malthus and Paul Ehrlich to celebrities from Bill Maher to Tucker ...

View more: “Time inequality” is the world’s real problem, not income inequality

The key to curing cancer in humans may be discovered in dogs

The key to curing cancer may be hidden within the genetic differences between humans and dogs. According to scientists working with the National Institutes of Health, dogs get the same diseases that we do, and they have many of the same genes that we do, too. However, in the last ...

View more: The key to curing cancer in humans may be discovered in dogs

Good Sleep Can Increase Women’s Ambitions

On days after a night of bad sleep, women indicated reduced aspirations to achieve higher status at work. Sleep quality impacts women’s daily intentions to pursue workplace status. Women may wish to lay down for a full night’s sleep before leaning into work. Research from Washington State University found ...

View more: Good Sleep Can Increase Women’s Ambitions

Psychologist debunks 8 myths of mass scale - Big Think

jQuery(function(){ if (typeof jwplayer_load == typeof indefined) { var jwplayer_load = 1; jQuery(window).load(function(){ jQuery(".sc_video_shortcode_jwplayer").each(function(){ var _this = $(this); jQuery.get(jQuery(this).attr("url"), function(data, status){ if (typeof data.split("\n") !== typeof undefined) { var src = data.split("\n")[4]; src = src.replace(".m3u8", ""); _this.attr("src", src); } }); }); }); } }); Collective illusions — false assumptions ...

View more: Psychologist debunks 8 myths of mass scale - Big Think

Mauna Loa Awakens – Satellites View World’s Largest Active Volcano

NOAA-NASA Suomi NPP satellite Visible Infrared Imaging Radiometer Suite (VIIRS) images of Hawaii on and . During Mauna Loa’s first eruption in nearly four decades, satellites observed the volcano’s nighttime glow and sulfur dioxide plume. Hawaii’s Mauna Loa—the world’s largest active volcano—has been quiet for the past four decades. But ...

View more: Mauna Loa Awakens – Satellites View World’s Largest Active Volcano

Resurrecting Billon-Year-Old Enzymes – Scientists Reveal New Key Information About Photosynthesis

As the Arctic warms, beavers are moving in

Does Marine Conservation Mitigate Climate Change?

Scientists call for action to help sunflower sea stars

Strong quake shakes main Indonesia island, no major damage

Indonesia villagers race to escape eruption as sky turns black

Making science more accessible to people with disabilities

Scientific Weight Loss Study: Green Mediterranean Diet Reduces Twice As Much Visceral Fat

NASA Astronauts Complete New Solar Array Installation on International Space Station

New toothy diving dinosaur discovered

NASA Artemis I – Flight Day 18: Orion Spacecraft Re-enters Lunar Sphere of Influence

Johns Hopkins Researchers Have Identified a Potential New Treatment Target for Sleep Apnea

OTHER TECH NEWS

Top Car News Car News